136759-00-7

Basic information

• Product Name: N-[(2(S) 7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]-(2R)-2-hydroxy-2-(3-chlorophenyl)ethanamine hydrochloride
• Synonyms: N-[(2(S) 7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]-(2R)-2-hydroxy-2-(3-chlorophenyl)ethanamine hydrochloride
• CAS NO: 136759-00-7
• Molecular Weight: 382.33
• Mol File: 136759-00-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[(2(S) 7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]-(2R)-2-hydroxy-2-(3-chlorophenyl)ethanamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(2(S) 7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]-(2R)-2-hydroxy-2-(3-chlorophenyl)ethanamine hydrochloride(136759-00-7)
• EPA Substance Registry System: N-[(2(S) 7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)methyl]-(2R)-2-hydroxy-2-(3-chlorophenyl)ethanamine hydrochloride(136759-00-7)

Safety Data

• Hazardous Substances Data: 136759-00-7(Hazardous Substances Data)

Upstream product

• 20697-04-5 (R)-meta-chlorostyrene oxide 

Relevant articles and documents

Phenylethanolaminomethyltetralins and pharmaceutical use

New phenylethanolaminomethyltetralins of formula (I) STR1 wherein E represents hydrogen, (C1 -C4)alkyl, (C1 -C4)alkoxy, phenyl, nitro, halogen, or trifluoromethyl, L represents hydrogen, (C1 -C4)alkyl, (C1 -C4)alkyoxy, phenyl, nitro, or halogen, or E and L taken together represent a group --CH=CH--CH=CH-- or --CH2 --CH2 --CH2 --CH2 --, and G represents hydrogen, chloro, hydroxy or an --OG' group wherein G' represents a (C1 -C4 (alkyl group either unsubstituted or substituted with hydroxy, (C1 -C4)alkoxy, (C1 -C4)alkoxycarbonyl, carboxy, or (C3 -C7)cycloalkyl; a (C3 -C7)cycloalkyl group; or a (C2 -C4)alkanoyl group; and salts thereof, are described which showed to be active as intestinal motility modulating agents and intraocular hypertension lowering agents. Also described is a process for the preparation of the new compounds and the intermediates of formula (III) STR2 employed in said process.