13676-48-7

Basic information

• Product Name: 5-Amino-2-(3-aminophenyl)benzoxazole
• Synonyms: 5-Amino-2-(3-aminophenyl)benzoxazole;5-Amino-2-(m-aminophenyl)benzoxazole
• CAS NO: 13676-48-7
• Molecular Formula: C₁₃H₁₁N₃O
• Molecular Weight: 225.25
• Product Categories: Chemical Amines;Amines;Aromatics;Heterocycles
• Mol File: 13676-48-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 450 °C at 760 mmHg
• Flash Point: 225.9 °C
• Appearance: /
• Density: 1.329 g/cm³
• Vapor Pressure: 2.74E-08mmHg at 25°C
• Refractive Index: 1.729
• CAS DataBase Reference: 5-Amino-2-(3-aminophenyl)benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Amino-2-(3-aminophenyl)benzoxazole(13676-48-7)
• EPA Substance Registry System: 5-Amino-2-(3-aminophenyl)benzoxazole(13676-48-7)

Safety Data

• Hazardous Substances Data: 13676-48-7(Hazardous Substances Data)

Usage

Description

5-Amino-2-(3-aminophenyl)benzoxazole is a heterocyclic chemical compound with the molecular formula C13H11N3O. It is a benzoxazole derivative characterized by the fusion of a benzene ring with an oxazole ring, featuring two amino groups and a substituted phenyl group. 5-Amino-2-(3-aminophenyl)benzoxazole holds potential for applications in the pharmaceutical industry, particularly in the development of drugs with biological activity, due to its unique structure and properties.

Uses

Used in Pharmaceutical Industry:
5-Amino-2-(3-aminophenyl)benzoxazole is used as a potential component in drug discovery and development for its ability to contribute to the creation of drugs with biological activity. Its unique structure and properties make it a candidate for further study and potential incorporation into novel therapeutic agents.
Used in Drug Development:
5-Amino-2-(3-aminophenyl)benzoxazole is utilized as a building block in the synthesis of new pharmaceutical compounds, given its heterocyclic nature and the presence of reactive amino groups that can be further modified or used in chemical reactions to produce bioactive molecules.
Used in Medicinal Chemistry Research:
As a heterocyclic compound with specific functional groups, 5-Amino-2-(3-aminophenyl)benzoxazole is used in medicinal chemistry research to explore its interactions with biological targets, potentially leading to the discovery of new drugs with improved efficacy and selectivity.
Used in Chemical Synthesis:
5-Amino-2-(3-aminophenyl)benzoxazole serves as a versatile intermediate in organic synthesis, particularly for the preparation of various benzoxazole-based compounds that may have applications in different fields, including pharmaceuticals, materials science, and agrochemicals.
Used in Biochemical Studies:
5-Amino-2-(3-aminophenyl)benzoxazole is also used in biochemical studies to investigate its binding affinity and selectivity towards specific enzymes or receptors, which can provide insights into its potential therapeutic applications and mechanisms of action.

InChI:InChI=1/C13H11N3O/c14-9-3-1-2-8(6-9)13-16-11-7-10(15)4-5-12(11)17-13/h1-7H,14-15H2

Upstream product

• 137-09-7 2,4-diaminophenol dihydrochloride 
• 99-05-8 meta-aminobenzoic acid 
• 99-57-0 2-hydroxy-5-nitroaniline 
• 121-90-4 m-nitrobenzoic acid chloride 
• 105753-07-9 C₁₃H₉N₃O₆ 

Downstream Products

• 1033093-54-7 C₃₁H₄₅N₅O₃ 

Relevant articles and documents

Effect of isomerism on molecular packing and gas transport properties of poly(benzoxazole-co-imide)s

A facile approach to synthesize poly(benzoxazole-co-imide)s without thermal rearrangement at high temperature is proposed. Poly(benzoxazole-co-imide)s with improved mechanical and solution-processable properties were prepared through polycondensation of 4

Gelation-induced fluorescence enhancement of benzoxazole-based organogel and its naked-eye fluoride detection

The benzoxazole derivative gelator 1 forms a stable DMF/toluene cosolvent gel with dramatically enhanced fluorescence emission compared to its mother solution. The translucent colorless gel was changed to a solution with strong greenish fluorescence in th

Process for making 2-aryl benz (ox, thi, imid)azoles and 2-aminoaryl aminobenz(ox, thi, imid)azoles

2-(aryl)-benz(ox, thi, imid)azoles are prepared by reacting an aromatic aldehyde with hydroxylamine to form an aromatic aldehyde oxime, halogenating the oxime to form an aromatic hydroxamoyl halide, and then reacting this halide with certain aromatic amine compounds. The products may be nitrated and then reduced to form the corresponding diamines, which are useful in making PIBX polymers.