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Usage

Uses

Used in Pharmaceutical Industry:
5-Amino-2-(3-aminophenyl)benzoxazole is used as a potential component in drug discovery and development for its ability to contribute to the creation of drugs with biological activity. Its unique structure and properties make it a candidate for further study and potential incorporation into novel therapeutic agents.
Used in Drug Development:
5-Amino-2-(3-aminophenyl)benzoxazole is utilized as a building block in the synthesis of new pharmaceutical compounds, given its heterocyclic nature and the presence of reactive amino groups that can be further modified or used in chemical reactions to produce bioactive molecules.
Used in Medicinal Chemistry Research:
As a heterocyclic compound with specific functional groups, 5-Amino-2-(3-aminophenyl)benzoxazole is used in medicinal chemistry research to explore its interactions with biological targets, potentially leading to the discovery of new drugs with improved efficacy and selectivity.
Used in Chemical Synthesis:
5-Amino-2-(3-aminophenyl)benzoxazole serves as a versatile intermediate in organic synthesis, particularly for the preparation of various benzoxazole-based compounds that may have applications in different fields, including pharmaceuticals, materials science, and agrochemicals.
Used in Biochemical Studies:
5-Amino-2-(3-aminophenyl)benzoxazole is also used in biochemical studies to investigate its binding affinity and selectivity towards specific enzymes or receptors, which can provide insights into its potential therapeutic applications and mechanisms of action.

InChI:InChI=1/C13H11N3O/c14-9-3-1-2-8(6-9)13-16-11-7-10(15)4-5-12(11)17-13/h1-7H,14-15H2

Upstream product

• 137-09-7 2,4-diaminophenol dihydrochloride 
• 99-05-8 meta-aminobenzoic acid 
• 99-57-0 2-hydroxy-5-nitroaniline 
• 121-90-4 m-nitrobenzoic acid chloride 
• 105753-07-9 C₁₃H₉N₃O₆ 

Downstream Products

• 1033093-54-7 C₃₁H₄₅N₅O₃ 

Relevant academic research and scientific papers

Effect of isomerism on molecular packing and gas transport properties of poly(benzoxazole-co-imide)s

A facile approach to synthesize poly(benzoxazole-co-imide)s without thermal rearrangement at high temperature is proposed. Poly(benzoxazole-co-imide)s with improved mechanical and solution-processable properties were prepared through polycondensation of 4

Preparation method of 2-aminobenzoxazole compound

The present invention relates to a method for preparing a 2-aminobenzoxazole compound. Comprising the following steps: (1) condensation reaction: taking o-aminophenol and nitrobenzoyl chloride compounds as raw materials, synthesizing amide intermediates in an alkaline solution system. The highly selective double-base combination system does not react with the raw material and can neutralize the acid gas generated by the reaction; (2) Cyclization reaction: acid is added to the condensation reaction solution as a catalyst, and 2-nitrobenzoxazole compounds are generated after dehydration. The solid super acid catalyst used is efficient and easy to separate and recycle; (3) hydrogenation hydrogenation reaction: 2-nitrobenzoxazole compounds are catalyzed to obtain 2-aminobenzoxazole compounds. The bi-alkali system and solid super acids used in the present invention are highly selective, product quality and yield are high. The operation is safe and simple, the raw material cost is low, in line with the green and environmentally friendly production concept, which is conducive to industrial production.

Gelation-induced fluorescence enhancement of benzoxazole-based organogel and its naked-eye fluoride detection

The benzoxazole derivative gelator 1 forms a stable DMF/toluene cosolvent gel with dramatically enhanced fluorescence emission compared to its mother solution. The translucent colorless gel was changed to a solution with strong greenish fluorescence in th

Process for making 2-aryl benz (ox, thi, imid) azoles and 2-aminoaryl aminobenz (ox, thi, imid) azoles

2-(aryl)-benz(ox, thi, imid)azoles are prepared by reacting an aromatic aldehyde with hydroxylamine to form an aromatic aldehyde oxime, halogenating the oxime to form an aromatic hydroxamoyl halide, and then reacting this halide with certain aromatic amine compounds. The products may be nitrated and then reduced to form the corresponding diamines, which are useful in making PIBX polymers.

Process for making 2-aryl benz (ox, thi, imid)azoles and 2-aminoaryl aminobenz(ox, thi, imid)azoles

2-(aryl)-benz(ox, thi, imid)azoles are prepared by reacting an aromatic aldehyde with hydroxylamine to form an aromatic aldehyde oxime, halogenating the oxime to form an aromatic hydroxamoyl halide, and then reacting this halide with certain aromatic amine compounds. The products may be nitrated and then reduced to form the corresponding diamines, which are useful in making PIBX polymers.