1367695-96-2Relevant academic research and scientific papers
Novel phosphate derivatives as scaffolds for the preparation of synthetic phosphoserine-based peptides using the Fmoc/ t -Bu solid-phase strategy
Cilibrizzi, Agostino,Isidro-Llobet, Albert,Mateu, Natalia,Galloway, Warren R. J. D.,Spring, David R.
, p. 290 - 294 (2012)
Synthetic peptides incorporating analogues of phosphoserine are valuable tools for the study of protein kinases and phosphatases. In addition, derivatives of naturally occurring peptides incorporating phosphate groups may have interesting biological properties. Herein we describe a new Fmoc/t-Bu solid-phase peptide synthesis (SPPS) strategy for the convenient generation of phosphoserine-based peptides. A proof-of-concept synthesis that demonstrates the feasibility of this approach is presented. Georg Thieme Verlag Stuttgart - New York.
