136773-67-6

Basic information

• Product Name: Pyrrolo[1,2-a]quinoxalin-4(5H)-one,7-fluoro-
• Synonyms: Pyrrolo[1,2-a]quinoxalin-4(5H)-one,7-fluoro-;7-fluoro-5H-pyrrolo[1,2-a]quinoxalin-4-one;7-Fluoropyrrolo[1,2-a]quinoxalin-4(5H)-one
• CAS NO: 136773-67-6
• Molecular Formula: C11H7FN2O
• Molecular Weight: 202.18
• Product Categories: Drug Intermediates
• Mol File: 136773-67-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 237.7±33.0 °C(Predicted)
• Appearance: /
• Density: 1.44±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 11.12±0.20(Predicted)
• CAS DataBase Reference: Pyrrolo[1,2-a]quinoxalin-4(5H)-one,7-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[1,2-a]quinoxalin-4(5H)-one,7-fluoro-(136773-67-6)
• EPA Substance Registry System: Pyrrolo[1,2-a]quinoxalin-4(5H)-one,7-fluoro-(136773-67-6)

Safety Data

• Hazardous Substances Data: 136773-67-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 21, p. 1567, 1991 DOI: 10.1080/00397919108021054

Upstream product

• 364-74-9 1,4-difluoro-2-nitrobenzene 
• 1193-62-0 methyl Pyrrole-2-carboxylate 
• 896429-57-5 5-fluoro-2-(1H-pyrrol-1-yl)aniline 
• 1373758-54-3 3-(4-methylphenyl)-5H-1,4,2-dioxazol-5-one 
• 367-25-9 2,4-difluorophenylamine 
• 136773-61-0 1-(2,4-difluorophenyl)-1H-pyrrole-2-carbonitrile 
• 125126-63-8 1-(2,4-difluorophenyl)-1H-pyrrole 

Downstream Products

• 136773-69-8 7-fluoro-4-chloropyrrolo[1,2-a]quinoxaline 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN

Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, especially huntingtin protein aggregation, compositions thereof, and methods of their use.

Polycondensed heterocycles. VII. A convenient synthesis of pyrrolo[1,2-a]quinoxaline derivatives by intramolecular aromatic nucleophilic displacement

4-(4-Methyl-1-piperazinyl)-7- trifluoromethylpyrrolo[1,2-a]quinoxaline (CGS 12066B) and related analogs were prepared in good overall yield through a reaction sequence involving as a key step in the intramolecular substitution of aromatic fluoride or nitr