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Abacavir Sulfate is a potent nucleoside reverse transcriptase inhibitor (NRTI) that plays a crucial role in the treatment of HIV/AIDS. It functions by disrupting the activity of reverse transcriptase, an enzyme essential for the virus's replication and multiplication within the body. This medication is commonly administered in conjunction with other antiretroviral drugs to effectively control the disease's progression.

136777-48-5

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136777-48-5 Usage

Uses

Used in Pharmaceutical Industry:
Abacavir Sulfate is used as an antiretroviral medication for the treatment of HIV/AIDS. It is employed to inhibit the replication of the virus, thereby slowing down the progression of the disease and improving the quality of life for patients.
Used in Combination Therapy:
Abacavir Sulfate is used as a component of combination therapy for HIV/AIDS. It is combined with other antiretroviral medications to enhance the effectiveness of treatment and reduce the likelihood of the virus developing resistance to the drugs.
Used in HLA-B5701 Screening:
Abacavir Sulfate is used as a reference in the screening of patients for the HLA-B5701 allele. This genetic screening is crucial as individuals carrying this gene are at a higher risk of experiencing severe hypersensitivity reactions to the medication, and alternative treatment options may be considered for them.
Used in Management of Adverse Effects:
Abacavir Sulfate is used in the management of adverse effects associated with its use, such as hypersensitivity reactions, liver problems, and lactic acidosis. Monitoring and appropriate interventions are necessary to ensure the safe and effective use of the medication in patients.

Check Digit Verification of cas no

The CAS Registry Mumber 136777-48-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,7,7 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 136777-48:
(8*1)+(7*3)+(6*6)+(5*7)+(4*7)+(3*7)+(2*4)+(1*8)=165
165 % 10 = 5
So 136777-48-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H18N6O/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19)/t8-,10+/m0/s1

136777-48-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [(4S)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopenten-1-yl]methanol,sulfuric acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:136777-48-5 SDS

136777-48-5Upstream product

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