136778-39-7

Basic information

• Product Name: 7-goniofufurone
• Synonyms: 7-goniofufurone
• CAS NO: 136778-39-7
• Molecular Formula: C₁₃H₁₄O₅
• Molecular Weight: 250.24726
• Mol File: 136778-39-7.mol
• Article Data: 29

Chemical Properties

• Melting Point: 192-193 °C
• Boiling Point: 527.1°Cat760mmHg
• Flash Point: 208.5°C
• Appearance: /
• Density: 1.429g/cm³
• Vapor Pressure: 6.12E-12mmHg at 25°C
• Refractive Index: 1.618
• PKA: 13.15±0.40(Predicted)
• CAS DataBase Reference: 7-goniofufurone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-goniofufurone(136778-39-7)
• EPA Substance Registry System: 7-goniofufurone(136778-39-7)

Safety Data

• Hazardous Substances Data: 136778-39-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H14O5/c14-9-6-8-12(18-9)11(16)13(17-8)10(15)7-4-2-1-3-5-7/h1-5,8,10-13,15-16H,6H2/t8-,10?,11-,12+,13-/m1/s1

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 96405-62-8 (5S,6R)-6-[(1S,2R)-1-(benzyloxy)-1,2-dihydroxy-2-phenylethyl]-5-hydroxy-5,6-dihydro-2H-pyran-2-one 
• 956317-01-4 3,6-anhydro-5-O-benzyl-2-deoxy-7-C-phenyl-D-glycero-D-ido-heptono-1,4-lactone 
• 147697-41-4 3,6-anhydro-5,7-di-O-benzyl-2-deoxy-7-C-phenyl-D-glycero-D-ido-heptono-1,4-lactone 
• 144402-15-3 6R,7R,8S-7-benzyloxy-1,5-dioxa-6-(R-benzyloxybenzyl)-2-oxobicyclo<3.3.0.>oct-3-ene 
• 142955-65-5 (S)-5-((1S,2R,3R)-1,2,3-trihydroxy-3-phenylpropyl)furan-2(5H)-one 
• 134639-65-9 (2,3),(5,6)-bisacetonide-D-gluconic acid methylester 
• 1142892-78-1 (3R,3aS,6aR)-(2,3,3a,6a-tetrahydrofuro[3,2-b]furan-3-yl) acetate 
• 641-74-7 1,4:3,6-dianhydro-D-mannitol 
• 100-52-7 benzaldehyde 
• 1262487-65-9 (3aR,5S,6S,6aR)-5-((R)-benzyloxy(phenyl)methyl)-6-hydroxy-tetrahydrofuro[3,2-b]furan-2(5H)-one 
• 1262487-68-2 (3aR,5R,6S,6aS)-6-allyloxy-5-((R)-hydroxy(phenyl)methyl)-tetrahydrofuro[3,2-b]furan-2(5H)-one 

Downstream Products

• 1262487-80-8 (R)-((2R,3S,3aS,6aR)-3-(cinnamoyloxy)-5-oxo-hexahydrofuro[3,2-b]furan-2-yl)(phenyl)methyl cinnamate 
• 129578-09-2 diacetylgoniofufurone 

Relevant articles and documents

A concise synthesis of (+)-goniofufurone, (+)-7-epi-goniofufurone, (+)-crassalactones B and C

The concise and efficient synthesis of (+)-goniofufurone, (+)-7-epi-goniofufurone, (+)-crassalactones B and C were achieved in 6 to 7 steps from the known D-glucono-δ-lactone derivative 9. An acid-mediated cascade cyclization was employed to construct the

Conformationally constrained goniofufurone mimics as inhibitors of tumour cells growth: Design, synthesis and SAR study

Synthesis of conformationally restricted (+)-goniofufurone (1) and 7-epi-(+)-goniofufurone (2) analogues, with embedded O-isopropylidene, O-methylidene or cyclic carbonate functions is disclosed starting from d-glucose. A number of potential bioisosteres

Design, synthesis and antiproliferative activity of styryl lactones related to (+)-goniofufurone

This paper describes a straightforward divergent synthesis of (+)-goniofufurone mimics (4, 5 and 6) starting from d-xylose. In a preliminary bioassay, analogues 4 and 5 exhibited a submicromolar antiproliferative activity towards HL-60 cells, while the co