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Usage

Uses

Used in Coordination Chemistry:
1-(2-thienyl)propane-1,2-dione is used as a chelating agent for its ability to bind to metal ions, which is instrumental in catalysis, metal extraction, and material science.
Used in Pharmaceutical Synthesis:
As a precursor, 1-(2-thienyl)propane-1,2-dione is utilized in the synthesis of pharmaceuticals, contributing to the development of new medications.
Used in Organic Compound Synthesis:
1-(2-thienyl)propane-1,2-dione also serves as a precursor in the synthesis of various organic compounds, expanding its utility in organic chemistry.
Used in Fluorescence Sensing and Probes:
Due to its unique properties, 1-(2-thienyl)propane-1,2-dione has potential applications in the field of fluorescence sensing and the creation of fluorescent probes, which are important tools in analytical chemistry and biochemistry.

InChI:InChI=1/C7H6O2S/c1-5(8)7(9)6-3-2-4-10-6/h2-4H,1H3

Upstream product

• 3051-27-2 1-(2-thienyl)-1,3-butanedione 
• 15022-18-1 1-(thiophen-2-yl)propan-2-one 
• 1346260-46-5 (E)-2-(methoxyimino)-1-(thiophen-2-yl)propan-1-one 
• 96514-32-8 C₈H₇NOS 

Downstream Products

• 107486-55-5 2,5-Dimethyl-1-hydroxy-4-phenyl-2-(thenoyl-2)-3-imidazoline 3-oxide 

Relevant academic research and scientific papers

Copper-catalyzed TEMPO oxidative cleavage of 1,3-diketones and β-keto esters for the synthesis of 1,2-diketones and α-keto esters

A copper-catalyzed efficient and practical method has been developed for the synthesis of 1,2-diketones and α-keto esters. TEMPO was used as a radical initiator and scavenger, oxidizing the cleavage of α-methylene of 1,3-diketones and β-keto esters to form 1,2-diketones and α-keto esters. This method provided a general way for the formation of 1,2-dicarbonyl compounds.

PPh3·HBr-DMSO: A Reagent System for Diverse Chemoselective Transformations

The broad applicability of the hitherto unexplored reagent combination PPh3·HBr-DMSO is exemplified with multiple highly diverse one-step transformations to synthetically useful building blocks, such as flavones, 4H-thiochromen-4-ones, α-hydroxy ketones, 1,4-naphthoquinones (including vitamin K3), 2-bromo-3-substituted-1H-1-indenones, 2-methylthio-1H-1-indenones, 3-butyne-1,2-dione, and 4-pentene-2,3-diones. The simple and mild reaction conditions make the reagent superior in terms of yield and substrate scope in comparison with the existing alternatives.

Synthesis of 1,2-diketones from β-keto nitriles via a protection-oxidative-decyanation-deprotection protocol

A variety of 1,2-diketones were prepared from -keto nitriles via a three-step protocol including the protection of the ketones with methoxyamine, oxidative decyanation, and microwave-assisted deprotection in the final step. This approach provides a novel and efficient access to a wide scope of symmetric and unsymmetric 1,2-diketones using molecular oxygen as the oxidant in the decyanation process. Georg Thieme Verlag Stuttgart - New York.