1368127-45-0

Basic information

• Product Name: 4-chloro-2-(imidazo[1,2-a]pyridine-2-yl)phenol
• Synonyms: 4-chloro-2-(imidazo[1,2-a]pyridine-2-yl)phenol
• CAS NO: 1368127-45-0
• Molecular Weight: 244.68
• Mol File: 1368127-45-0.mol

Chemical Properties

• CAS DataBase Reference: 4-chloro-2-(imidazo[1,2-a]pyridine-2-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-2-(imidazo[1,2-a]pyridine-2-yl)phenol(1368127-45-0)
• EPA Substance Registry System: 4-chloro-2-(imidazo[1,2-a]pyridine-2-yl)phenol(1368127-45-0)

Safety Data

• Hazardous Substances Data: 1368127-45-0(Hazardous Substances Data)

Upstream product

• 504-29-0 2-aminopyridine 
• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 52727-99-8 2-bromo-1-(5-chloro-2-hydroxyphenyl)-1-ethanone 

Relevant articles and documents

One-Pot Three-Component Synthesis of Alkylthio-/Arylthio- Substituted Imidazo[1,2-a]pyridine Derivatives via C(sp2)–H Functionalization

Sulfenylation is an important transformation to generate C?S bonds in organic synthesis. Here, two three-component synthetic protocols have been developed by using imidazo[1,2-a]pyridine, inorganic, odorless S8 and alcohols or arylboronic acids

Iodine–ammonium acetate promoted reaction between 2-aminopyridine and aryl methyl ketones: a novel approach towards the synthesis of 2-arylimidazo[1,2-a]pyridines

I2–NH4OAc was found to be an efficient system for the metal-free synthesis of diversely substituted imidazo[1,2-a]pyridines 3a–r from 2-aminopyridine 1 and aryl methyl ketones 2a–r in one pot. 2-Arylimidazo[1,2-a]pyridines 3a–r were

Electrochemically initiated intermolecular C-N formation/cyclization of ketones with 2-aminopyridines: An efficient method for the synthesis of imidazo[1,2-: A] pyridines

Electrochemical intermolecular C-N formation/cyclization of ketones with 2-aminopyridines using catalytic hydriodic acid as the redox mediator was developed, providing imidazo[1,2-a]pyridines under more environmentally benign conditions. The reaction proceeds in a simple undivided cell, using low toxic ethanol as the solvent, without external oxidants, and exhibits high atom economy. A variety of ketones including acetophenones, unsatruated and alkyl ketones are amenable to this reaction, affording the corresponding products in moderate to excellent yields. A three-component tandem reaction realizing C-N, C-S/C-Se bond formation can also be achieved under standard conditions.

Tuning of excited-state intramolecular proton transfer (ESIPT) fluorescence of imidazo[1,2-a]pyridine in rigid matrices by substitution effect

2-(2′-Hydroxyphenyl)imidazo[1,2-a]pyridine (HPIP, 1) and its derivatives are synthesized, and their fluorescence properties are studied. Although all the compounds show faint dual emission (Φ ≈ 0.01), which is assigned to the normal and excited-state intr