136843-92-0

Basic information

• Product Name: 6,6-Dimethyl-5-oxo-3-phenyl-heptanoic acid tert-butyl ester
• CAS NO: 136843-92-0
• Molecular Weight: 304.43
• Mol File: 136843-92-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6,6-Dimethyl-5-oxo-3-phenyl-heptanoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6,6-Dimethyl-5-oxo-3-phenyl-heptanoic acid tert-butyl ester(136843-92-0)
• EPA Substance Registry System: 6,6-Dimethyl-5-oxo-3-phenyl-heptanoic acid tert-butyl ester(136843-92-0)

Safety Data

• Hazardous Substances Data: 136843-92-0(Hazardous Substances Data)

Upstream product

• 76906-48-4 4-(2-bromo-1-tert-butyl-vinyl)-morpholine 
• 14990-09-1 tert-butyl cinnamate 
• 22502-84-7 4-(1-t-butylethenyl)morpholine 

Relevant articles and documents

β-Lithiated enamines as enolate equivalents in Michael additions to enoates. A novel entry to mono- and disubstituted 5-oxo esters

Mono-, di- and trisubstituted tert-butyl 5-amino-4-alkenoates 3 and mono- or disubstituted tert-butyl 5-oxoalkanoates 4 are prepared in good overall yield by conjugate addition of β-lithiated enamines to enoates, followed by quenching with water or iodomethane. In all cases, only one stereoisomer of the polysubstituted enamino esters 3 is produced (de > 98%).