136846-19-0

Basic information

• Product Name: (-)-(2S,5S)-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>-N₄-acetylcystosine
• Synonyms: (-)-(2S,5S)-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>-N₄-acetylcystosine
• CAS NO: 136846-19-0
• Molecular Weight: 509.701
• Mol File: 136846-19-0.mol

Chemical Properties

• CAS DataBase Reference: (-)-(2S,5S)-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>-N₄-acetylcystosine(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(2S,5S)-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>-N₄-acetylcystosine(136846-19-0)
• EPA Substance Registry System: (-)-(2S,5S)-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>-N₄-acetylcystosine(136846-19-0)

Safety Data

• Hazardous Substances Data: 136846-19-0(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 148774-90-7 (2S,5S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-[1,3]oxathiolane-5-carbaldehyde 
• 14631-20-0 4-N-Acetylcytosine 
• 202532-88-5 <2S(2α,5α)>- and <2S(2α,5β)>-2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-ol acetate 
• 54230-57-8 N⁴-acetyl-O-trimethylsilylcytosine 
• 140436-33-5 (-)-<2S(2α,5α)>-2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolane-5-methanol 5-benzoate 
• 140436-34-6 (-)-<2S(2α,5α)>-2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolane-5-methanol 
• 136794-46-2 <2S,(2α,3β,5α)>- and <2S(2α,3α,5α)>-2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolane-5-carboxylic acid methyl ester 3-oxide 
• 136794-47-3 <2S(2α,5α)>-2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolane-5-carboxylic acid methyl ester 
• 140630-83-7 (-)-<2S(2α,5α)>-2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolane-5-carboxylic acid 

Downstream Products

• 136846-20-3 (2S,5S)-1-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine 
• 149819-22-7 (-)-(2S,5S)-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>-cystosine 

Relevant articles and documents

Structure-Activity Relationships of β-D-(2S,5R)- and α-D-(2S,5S)-1,3-oxathiolanyl Nucleosides as Potential Anti-HIV Agents

The β-D-(2S,5R)- and α-D-(2S,5S)-1,3-oxathiolanylpyrimidine and -purine nucleosides with natural nucleoside configuration were synthesized and evaluated against HIV-1 in human peripheral blood mononuclear (PBM) cells.The key intermediate 14, which was uti

An efficient synthesis of enantiomerically pure (+)-(2S,5R)-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine [(+)-BCH-189] from d-galactose

An efficient and short synthesis of enantiomerically pure (+)-BCH-189 has been accomplished from D-galactose via 1,6-thioanhydro-D-galactose.

Enantiomeric Synthesis of (+)-BCH-189 cytosine> from D-Mannose and Its Anti-HIV Activity

Enantiomerically pure (+)-BCH-189 has been synthesized from D-mannose via 1,6-thioanhydro-D-mannose and its anti-HIV activity has been determined in peripheral blood mononuclear cells.