136849-93-9Relevant academic research and scientific papers
A Unified Synthesis of Bifunctional 4-Substituted-1,2,3,4-tetrahydroisoquinoline Derivatives
Bernabeu, M. Carmen,Diaz, Jose Luis,Jimenez, Oscar,Lavilla, Rodolfo
, p. 137 - 149 (2007/10/03)
Starting from a single, commercially available bromoisoquinoline, convenient (multigram) syntheses of 4-substituted-1,2,3, 4-tetrahydroisoquinoline derivatives have been developed. The compounds thus prepared show suitable substitution patterns for further derivatization and constitute a new family of compounds of potential pharmacological interest.
