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8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE is a derivative of 8-Oxo-2'-deoxyguanosine (O850250), a compound that serves as a biomarker for DNA damage linked to mutagenesis and carcinogenesis. This molecule has the potential to induce differentiation in certain cell types, such as Friend murine erythroleukemia cells in vitro.

136859-76-2

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136859-76-2 Usage

Uses

Used in Research Applications:
8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE is used as a research tool for studying the mechanisms of DNA damage, mutagenesis, and carcinogenesis. Its role in inducing differentiation of specific cell lines makes it a valuable compound for investigating cellular processes and potential therapeutic targets in cancer research.
Used in Diagnostic Applications:
As a marker compound for DNA damage, 8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE can be utilized in diagnostic assays to detect and monitor the presence of DNA damage in various conditions, including cancer. This can aid in the early detection of the disease and the assessment of treatment efficacy.
Used in Pharmaceutical Development:
8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE may also be used in the development of new pharmaceuticals targeting DNA repair mechanisms or as a potential therapeutic agent itself, particularly in the context of cancer treatment. Its ability to induce differentiation in certain cell lines could be harnessed to develop novel treatments for specific types of cancer.
Used in Anticancer Applications:
8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE is used as a potential anticancer agent due to its ability to induce differentiation in Friend murine erythroleukemia cells. This property may be exploited to develop targeted therapies for specific types of cancer, potentially improving patient outcomes and reducing the side effects associated with conventional chemotherapy.
Used in Drug Delivery Systems:
In the context of drug delivery, 8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE could be incorporated into novel drug delivery systems to enhance its bioavailability and therapeutic efficacy. This may involve the use of nanoparticles or other carriers to improve the delivery of the compound to target cells, potentially increasing its effectiveness in treating cancer and other diseases associated with DNA damage.

Check Digit Verification of cas no

The CAS Registry Mumber 136859-76-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,8,5 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 136859-76:
(8*1)+(7*3)+(6*6)+(5*8)+(4*5)+(3*9)+(2*7)+(1*6)=172
172 % 10 = 2
So 136859-76-2 is a valid CAS Registry Number.

136859-76-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,8-dioxo-3,7-dihydropurin-2-yl]-2-methylpropanamide

1.2 Other means of identification

Product number -
Other names 8-HYDROXY-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:136859-76-2 SDS

136859-76-2Upstream product

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