136885-84-2Relevant academic research and scientific papers
THERMAL TRANSFORMATIONS OF OXAZOLE ENDOPEROXIDES: REARRANGEMENTS, FRAGMENTATIONS AND METHANOL ADDITIONS
Gollnick, Klaus,Koegler, Sigrid
, p. 1007 - 1010 (2007/10/02)
Oxazole endoperoxides 1 carrying a phenyl group at C-2 rearrange to triacylamines 3; those carrying a hydrogen atom at C-2 undergo a fragmentation into 1:1 mixtures of nitriles (or HCN) 4 and anhydrides 5, whereas methyl substitution at C-2 gives rise to competition between these two modes of reaction.Methanol addition to 1 leads to 4-methoxy-5-hydroperoxides 6 which easily transform into methyl esters 7 and diacylamines 8.
