1369217-08-2

Upstream product

• 16520-62-0 4-Phenyl-1-butyne 
• 16817-43-9 5-Bromo-2-chloroanisole 
• 110463-12-2 4-chloro-3-methoxyphenylmethyl(triphenyl)phosphonium bromide 
• 1369217-07-1 C₂₄H₂₃ClN₂O₅S 
• 1369217-04-8 (+)-trans-N-[1-(4-chloro-3-methoxy-phenyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-4-nitro-benzenesulfonamide 
• 1369217-06-0 1-chloro-2-methoxy-4-(4-phenyl-but-1-enyl)-benzene 
• 7252-83-7 1-bromo-2,2-dimethoxyethane 
• 169249-10-9 (+)-trans-N-[1-(4-chloro-3-methoxy-phenyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-methylamine 
• 104-53-0 3-phenyl-propionaldehyde 

Relevant academic research and scientific papers

Catalytic enantioselective synthesis of the dopamine D1 antagonist ecopipam

A concise asymmetric synthesis of the potent dopamine D1 antagonist, ecopipam, has been accomplished in six steps with 33% overall yield via catalytic enantioselective aziridination and subsequent one-pot Friedel-Crafts cyclization of an in situ generated tethered aziridine with high diastereo- and enantioselectivities.