1369424-00-9

Upstream product

• 72-14-0 Sulfathiazole 
• 1158816-11-5 4-(4-cyanobenzoylamino)benzoyl chloride 
• 70586-66-2 4-(methylamino)-N-(thiazol-2-yl)benzenesulfonamide 
• 143330-23-8 4-[(4-cyanobenzoyl)amino]benzoic acid 
• 127442-05-1 ethyl 4-[N-(4-cyanobenzoyl)]-aminobenzoate 
• 6068-72-0 4-cyanobenzoyl chlorIde 
• 619-65-8 4-cyanobenzoic Acid 

Relevant academic research and scientific papers

arone and amide compound and its preparation and use in medicine

The invention discloses a novel arone and arylamide compound represented by formula I, a cistrans isomer, physiologically acceptable salts, a solvate and a crystallizing form thereof, a preparation method of the compound, a medicine preparation containing the compound and clinical application of the compound in treating diseases related to protein tyrosine phosphatases 1B.

Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors

Fifteen novel sulfathiazole-related compounds were designed as PTP1B inhibitors based on a previously reported allosteric inhibitor (1) of PTP1B. These compounds were synthesized and evaluated against human recombinant PTP1B. Six compounds (3, 4, 8 and 14