136944-06-4

Upstream product

• 274-09-9 Methylenedioxybenzene 
• 136944-01-9 2-Chloro-1-(3,4-dimethoxy-phenyl)-2-methylsulfanyl-ethanone 
• 67489-10-5 3,4-dimethoxy-α-(methylthio)acetophenone 

Downstream Products

• 136944-08-6 1-(benzo[1,3]dioxol-5-yl)-2-(3,4-dimethoxyphenyl)ethandione 

Relevant academic research and scientific papers

Synthesis of unsymmetrically substituted benzils via the Friedel-Crafts reaction of arenes with α-chloro-α-(methylthio)acetophenones

Lewis acid-promoted reactions of arenes with α-chloro-α-(methylthio)acetophenones gave the Friedel-Crafts reaction products, which were then treated with 3 molar eq of cupric chloride in aqueous acetone to afford the unsymmetrically substituted benzils.