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2-Propenamide, N-(4-butylphenyl)-3-(3,4-dihydroxyphenyl)-, (E)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

136944-20-2

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136944-20-2 Usage

Chemical Classification

Phloroglucinol derivative compound

Function

Plant Growth Regulator: Regulates plant growth processes.
Antioxidant: Prevents oxidation, thus protecting cells from damage.
Antimicrobial Agent: Inhibits the growth of microorganisms.
Therapeutic Agent:
Anti-inflammatory: Reduces inflammation in the body.
Anti-tumor: Inhibits the growth of tumors.
Neuroprotective: Protects neurons from damage or degeneration.

Potential Therapeutic Applications

Cardiovascular Diseases: Studied for potential use in treating cardiovascular conditions.
Osteoporosis: Investigated for prevention and treatment of osteoporosis.

Research Status

Ongoing research to explore and harness its full potential.

Limitations

Further research required to fully understand its applications and mechanisms of action.

Check Digit Verification of cas no

The CAS Registry Mumber 136944-20-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,9,4 and 4 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 136944-20:
(8*1)+(7*3)+(6*6)+(5*9)+(4*4)+(3*4)+(2*2)+(1*0)=142
142 % 10 = 2
So 136944-20-2 is a valid CAS Registry Number.

136944-20-2Downstream Products

136944-20-2Relevant academic research and scientific papers

Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis

Jo, Hyeju,Choi, Minho,Sim, Jaeuk,Viji, Mayavan,Li, Siyuan,Lee, Young Hee,Kim, Youngsoo,Seo, Seung-Yong,Zhou, Yuanyuan,Lee, Kiho,Kim, Wun-Jae,Hong, Jin Tae,Lee, Heesoon,Jung, Jae-Kyung

, p. 3374 - 3377 (2017)

We have disclosed our effort to develop caffeic acid derivatives as potent and non-toxic inhibitors of α-MSH-stimulated melanogenesis to treat pigmentation disorders and skin medication including a cosmetic skin-whitening agent. The SAR studies revealed t

Skin Whitening Composition Comprising Caffeic Acid Derivatives as the Active Ingredients

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Paragraph 0093; 0135-0139, (2020/02/11)

The present invention relates to a skin whitening composition containing a new caffeic acid derivative compound as an active ingredient. According to the present invention, the caffeic acid derivative compound can be developed for a skin whitening cosmetic product or for a medicine for the hyperpigmentation of melanin because having skin whitening activity by inhibiting the biosynthesis of melanin in melanocytes.

Novel Chlorogenic Acid Derivatives and Composition for Treating Inflammatory Disease Comprising the Same

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Paragraph 0235; 0236; 0237; 0238, (2017/08/02)

The present invention relates to a novel chlorogenic acid derivative compound having anti-inflammatory activities and an anti-inflammatory composition comprising the same as an active ingredient. The chlorogenic acid derivative compound of the present invention inhibits overproduction of nitrogen oxide (NO) induced by treating LPS in macrophage. The chlorogenic acid derivative compound of the present invention suppresses activation of NF-κB which is a signal transmission-mediated transcription factor significant in an oxidative stress and inflammation-promoting path. The chlorogenic acid derivative compound of the present invention can be developed as medicine for various inflammatory diseases by inhibiting overproduction of nitrogen oxide and activation of NF-κB.

Novel Chlorogenic Acid Derivatives and Composition for Treating Inflammatory Disease Comprising the Same

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Paragraph 0206-0210, (2021/05/22)

The present invention relates to a novel chlorogenic acid derivative compound having anti-inflammatory activities and to an anti-inflammatory composition including the same as an active ingredient. The chlorogenic acid derivative compound of the present invention controls the overproduction of nitrogen oxide (NO) derived by the treatment of LPS in histiocytes. The chlorogenic acid derivative compound of the present invention inhibits the activation of NF-κB which is an important signal transmittal intermediated transcription factor in oxidant stress and inflammation promoting routes. The chlorogenic acid derivative compound of the present invention has a high possibility of being developed into an agent for treating various inflammatory diseases by inhibiting the overproduction of NO and the activation of NF-κB.

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