1369486-52-1Relevant academic research and scientific papers
Unexpected synthesis of 3-(2-aminothiazol-5-yl)-3-arylpropanoates through a one-pot four-component procedure
Li, Zheng,Li, Yanbo
, p. 689 - 691 (2011)
The novel one-pot four-component reactions of 2-aminothiazole, aldehydes, Meldrum's acid and aliphatic alcohols were investigated, and a series of unexpected compounds, 3-(2-aminothiazol-5-yl)-3-arylpropanoates, were synthesised under catalyst-free conditions. The protocol has advantages of mild conditions, high yield and simple work-up procedure. Thiazoles are important in the field of organic and medicinal chemistry.
