1369558-80-4

Upstream product

• 120-72-9 indole 
• 1374416-20-2 C₁₃H₈ClNS₃ 
• 2037-31-2 3-chlorophenylthiol 
• 625-99-0 3-iodochlorobenzene 
• 19742-92-8 bis(3-chlorophenyl) disulfide 
• 2888-06-4 3-chlorophenylsulfonyl chloride 
• 496-15-1 1-indoline 

Relevant academic research and scientific papers

Flavin/I2-Catalyzed Aerobic Oxidative C–H Sulfenylation of Aryl-Fused Cyclic Amines

We report an aerobic oxidative C–H sulfenylation of aryl-fused cyclic amines with various thiols catalyzed by flavin/I2 for the first time. While flavin I catalyzed the C–H sulfenylation of indolines to afford 3-sulfenylindoles, flavin II enabl

Preparation method of indole sulfide compound

The invention discloses a preparation method of an indole sulfide compound. The preparation method is conducted according to the following steps that a catalyst, an indole reactant, hydrazine hydrate,substituted phenyl sulfonyl chloride and a solvent are

Direct, Metal-free C(sp2)?H Chalcogenation of Indoles and Imidazopyridines with Dichalcogenides Catalysed by KIO3

Herein, we report a greener protocol for the synthesis of 3-Se/S-indoles and imidazo[1,2-a]pyridines through direct C(sp2)?H bond chalcogenation of heteroarenes with half molar equivalents of different dichalcogenides, using KIO3 as a non-toxic, easy-to-handle catalyst and a stoichiometric amount of glycerol. The reaction features are high yields, based on atom economy, easy performance on gram-scale, metal- and solvent-free conditions as well as applicability to different types of N-heteroarenes.

Synthesis of 3-sulfenylindoles by Pd (II) nanoclusters confined within metal-organic framework fibers in aqueous solution

We have found that fibrous nanosilica (KCC-1) can used as a excellent support for the synthesis of highly sparse nanoparticles. KCC-1 has high surface area that was functionalized with 1,3-bis(dimethylthiocarbamoyloxy)benzene groups acting as the strong performers so that the Pd (II) was complex without aggregation on the fibers of the KCC-1 microspheres (KCC-1/BTB/Pd). For synthesis of 3-sulfenylindoles from aryl iodide, indoles, and thiourea used from the KCC-1/BTB/Pd NPs as a catalyst that showed excellent catalytic activities under green conditions. Compared with the traditional substrate, KCC-1/BTB/Pd substantially increases protection and the accessibility of the nanoparticle sites due to its three dimensional hierarchical structure.

Cs2CO3-Catalyzed Aerobic Oxidative Cross-Dehydrogenative Coupling of Thiols with Phosphonates and Arenes

An efficient Cs2CO3-catalyzed oxidative coupling of thiols with phosphonates and arenes that uses molecular oxygen as the oxidant is described. These reactions provide not only a novel alkali metal salt catalyzed aerobic oxidation, but also an efficient approach to thiophosphates and sulfenylarenes, which are ubiquitously found in pharmaceuticals and pesticides. The reaction proceeds under simple and mild reaction conditions, tolerates a wide range of functional groups, and is applicable to the late-stage synthesis and modification of bioactive molecules.

Metal-free, iodine-catalyzed regioselective sulfenylation of indoles with thiols

An iodine-catalyzed regioselective sulfenylation of indoles in the presence of DMSO has been presented. Various indoles can react with aryl thiols or alkyl thiols to afford their corresponding 3-sulfenylindoles in good to excellent yields. The notable fea

Iodine-catalyzed Direct Thiolation of Indoles with Thiols Leading to 3-Thioindoles Using Air as the Oxidant

Abstract: A simple and convenient method has been developed for the construction of 3-thioindoles via molecular iodine-catalyzed direct thiolation of indoles with thiols. The present protocol, which employs thiols as the thiolating agents, inexpensive mol

Copper(I) iodide catalyzed 3-sulfenylation of indoles with unsymmetric benzothiazolyl-containing disulfides at room temperature

A highly efficient protocol for the synthesis of 3-sulfenylindoles in moderate to excellent yields via the reaction of indoles with unsymmetric benzothiazolyl-containing disulfides is described. Copper(I) iodide is used as the catalyst and the reactions t