1369592-87-9Relevant academic research and scientific papers
DABCO-catalyzed synthesis of trifluoromethylated furans from propargyl alcohols and methyl 2-perfluoroalkynoate
Chong, Qinglei,Xin, Xiaoyi,Wang, Chunxiang,Wu, Fan,Wang, Haolong,Shi, Ji-Cheng,Wan, Boshun
, p. 2105 - 2110 (2014/04/03)
The DABCO-catalyzed reaction of propargyl alcohols with methyl 2-perfluoroalkynoate to give trifluoromethylated furans in up to 98% yield under mild conditions has been developed. The established allene-enol and control experiments indicate that the react
An efficient and general iron-catalyzed one-pot synthesis of furans via α-hydroxy ketones and activated alkynes
Cao, Hua,Zhan, Haiying,Wu, Jianyong,Zhong, Haiping,Lin, Yuanguang,Zhang, Hong
, p. 2318 - 2322 (2012/05/19)
A new practical and economical process for the synthesis of substituted furan derivatives has been developed by an FeCl3-catalyzed reaction of α-hydroxy ketones with activated alkynes. This methodology represents a highly efficient synthetic route to electron-deficient furans for which catalytic approaches are scarce. Furthermore, this transformation is associated with readily available substrates, good yields, and mild conditions. An efficient iron-catalyzed one-pot synthesis of polysubstituted furans has been developed from electron-deficient alkynes and α-hydroxy ketones under mild reaction conditions. This green and eco-friendly system has shown high catalytic activity in the synthesis of furan derivatives. The yields are good, and the scope of substrates is wide.
Palladium-catalyzed one-pot synthesis of polysubstituted furans from alkynoates and 2-yn-1-ols
Huang, Huawen,Jiang, Huanfeng,Cao, Hua,Zhao, Jinwu,Shi, Dabin
, p. 3135 - 3144 (2012/05/05)
Easily accessible propargyl vinyl ethers are found to be acyclic precursors to construct furan derivatives. According to the reactive behavior of the substrates and the regulation of reaction conditions, three synthetic routes to polysubstituted furans vi
