136964-88-0Relevant academic research and scientific papers
One-pot synthesis of enantiomerically pure N-protected allylic amines from N-protected α-amino esters
Silveira-Dorta, Gastón,álvarez-Méndez, Sergio J.,Martín, Víctor S.,Padrón, José M.
supporting information, p. 957 - 962 (2016/07/06)
An improved protocol for the synthesis of enantiomerically pure allylic amines is reported. N-Protected α-amino esters derived from natural amino acids were submitted to a one-pot tandem reduction-olefination process. The sequential reduction with DIBAL-H
Novel 1,4-Asymmetric Induction in Nucleophilic 1,2-Additions to Chiral γ-Amino Enals
Reetz, M. T.,Wang, Fan,Harms, K.
, p. 1309 - 1311 (2007/10/02)
γ-Dibenzylamino enals 3a with the E-configuration derived from amino acids 1 react diastereoselectively with cuprates in an unexpected 1,2-manner, while the analogues 3b with the Z-configuration undergo diastereoselective additions with organolithium reagents.
