136969-85-2 Usage
Chemical class
1,3-Benzodiazepine derivative
Functional groups
Carboxylic acid, ester, aromatic ring
Structure
Consists of a benzene ring fused to a diazepine ring, with a 4-methylphenyl group at the 2nd position and an ethyl ester group at the 4th position
Appearance
Likely a solid or crystalline substance
Solubility
Soluble in organic solvents like methanol, ethanol, and acetone
Stability
Stable under normal temperature and pressure, but sensitive to heat, light, and moisture
Reactivity
May react with strong acids, strong bases, and nucleophiles
Synthesis
Derived from benzodiazepine carboxylic acid and ethyl alcohol through an esterification reaction
Applications
Used as an intermediate in the synthesis of pharmaceutical drugs with sedative, hypnotic, and anxiolytic properties; also used in scientific research and development of new pharmaceutical compounds
Safety
Potential hazards include irritation to eyes, skin, and respiratory system; should be handled with care and proper safety measures
Regulatory status
May be subject to regulatory controls depending on the intended use and jurisdiction
Check Digit Verification of cas no
The CAS Registry Mumber 136969-85-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,9,6 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 136969-85:
(8*1)+(7*3)+(6*6)+(5*9)+(4*6)+(3*9)+(2*8)+(1*5)=182
182 % 10 = 2
So 136969-85-2 is a valid CAS Registry Number.
136969-85-2Relevant academic research and scientific papers
Preparation, Reactivity and Synthetic Applications of Bis(iminophosphoranes): New Entries to Fused 1,3,5-Benzotriazepines, 1,3-Benzodiazepines and Indole Derivatives
Molina, Pedro,Arques, Antonio,Alias, Asuncion,Vinader, M. Victoria,Foces-Foces, M. C.,Hernandez-Cano, F.
, p. 3091 - 3110 (2007/10/02)
An aza-Wittig-type reaction of bis(iminophosphorane) 2 with two moles of alkyl or aryl iso(thio)cyanates leads to indazolotriazolobenzotriazepines 7.The bis(iminiphosphorane) 4 reacts with aromatic iso(thio)cyanates to give
Iminophosphorane-mediated synthesis of functionalized indoles and 1,3-benzodiazepines
Molina,Arques,Alias,Vinader
, p. 4401 - 4404 (2007/10/02)
Aza Wittig-type reaction of bis(iminophosphorane) 2 with aromatic isocyanates leads to either indoles 5 or pyrimido[4,5-b]indoles 6, whereas with aliphatic isocyanates and acyl chlorides afforded pyrrolo[2,3-b]indoles 7 and 1,3-benzodiazepines 10 respectively.
