1369715-50-3Relevant academic research and scientific papers
A uronic acid analogue of isofagomine lactam as a nanomolar glucuronidase inhibitor
Lindb?ck, Emil,Zhou, You,López, óscar,Fernández-Bola?os, José G.,Pedersen, Christian Marcus,Bols, Mikael
, p. 2045 - 2047 (2012)
The synthesis of (3S,4R,5R)-3,4-dihydroxypiperidin-2-one-5-carboxylic acid ('isofagomine lactam uronate') from d-arabinose is reported. The product is a potent inhibitor in the low nanomolar range (Ki 36 nM) for bovine liver β-glucuronidase.
