136981-75-4Relevant academic research and scientific papers
Investigations on the Formation of 4-Aminobicyclo[2.2.2]octanones
Seebacher, Werner,Kroepfl, Dietmar,Belaj, Ferdinand,Saf, Robert,Huefner, Antje,Weis, Robert
, p. 676 - 688 (2007/10/03)
Benzylidene acetone reacts with thiocyanates derived from secondary amines in a one-pot reaction to give 4-aminobicyclo[2.2.2]octan-2-ones. The reaction mixture was investigated for the presence of possible intermediates using GC-MS. These intermediates -
Amine-catalyzed direct self Diels-Alder reactions of α,β-unsaturated ketones in water: Synthesis of pro-chiral cyclohexanones
Ramachary,Chowdari, Naidu S.,Barbas III, Carlos F.
, p. 6743 - 6746 (2007/10/03)
Amine-catalyzed direct self Diels-Alder reactions of α,β-unsaturated ketones have been developed. (S)-1-(2-Pyrrolidinyl-methyl)pyrrolidine, L-proline and pyrrolidine catalyzed the reaction of α,β-unsaturated ketones to provide cyclohexanone derivatives with good yield (up to 80%) in a single step via in situ-generation of 2-amino-1,3-butadienes and iminium ion-activated enones. Pro-chiral cyclohexanones were selectively prepared with pyrrolidine catalysis in water.
Cyclodimerization of α,β-unsaturated ketones catalyzed by lanthanoid tri-2-propoxides
Okano, Tamon,Ohno, Katsutoshi,Kiji, Jitsuo
, p. 1041 - 1042 (2007/10/03)
α,β-unsaturated ketones are cyclodimerized by the catalysis of lanthanoid tri-2-propoxides into substituted cycohexanones in good yields. The catalytic activity of the lanthanoids is fairly superior to those of the sodium or aluminum propoxides.
Michael Addition of Acyclic Lithium 1,3-Dien-2-olates with α,β-Unsaturated Esters, Ketones, and Diesters
Kanemasa, Shuji,Kumegawa, Masahiro,Wada, Eiji,Nomura, Masafumi
, p. 2990 - 3004 (2007/10/02)
The Michael addition of lithium 1,3-dien-2-olates with α,β-unsaturated carbonyl compounds is described.With α,β-unsaturated esters the reaction was reversible even at -78 deg C, while kinetically controlled with α,β-unsaturated ketones or alkylidenemalona
Annelation reactions of enaminones with ethyl acetoacetate. Studies on the β-carbonyl compounds connected with β-polyketides. XI
Takeuchi,Handa,Koyama,Kamata,Goto,Tobinaga
, p. 1655 - 1658 (2007/10/02)
Though condensation at either the carbonyl oxygen or the unsaturated carbon adjacent to nitrogen of enaminones can occur in the reaction with the active methylene of ethyl acetoacetate, the results obtained in the condensation reactions of the enaminones
The Double Michael Reaction of α,β-Unsaturated Ketones with Siloxydienes Catalyzed by Trityl Perchlorate Forming Six-Membered Ring Systems
Mukaiyama, Teruaki,Sagawa, Yukihiro,Kobayashi, Shu
, p. 1821 - 1824 (2007/10/02)
In the presence of a catalytic amount of trityl perchlorate, the double Michael reaction of α,β-unsaturated ketones with siloxydienes smoothly proceeds to afford six-membered ring systems stereoselectively in good yields.Decalin derivatives are also obtai
