1369810-80-9

Upstream product

• 1369810-69-4 tert-butyl (3S,4R)-3,4-bis(benzyloxy)-5-hydroxy-2-methylenepentylcarbamate 
• 1369810-71-8 (2R,3S)-2,3-bis(benzyloxy)-4-((tert-butoxycarbonylamino)methyl)pent-4-enyl methanesulfonate 
• 1369810-73-0 (3R,4S)-tert-butyl 3,4-bis(benzyloxy)-5-methylenepiperidine-1-carboxylate 
• 1369810-78-5 (3S,4R,5R)-tert-butyl 4,5-bis(benzyloxy)-3-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate 

Downstream Products

• 1369810-76-3 ((3R,4S,5R)-4,5-bis(benzyloxy)piperidin-3-yl)methyl acetate 
• 1369810-82-1 (3S,4R,5R)-tert-butyl 3-acetoxy-4,5-bis(benzyloxy)piperidine-1-carboxylate 

Relevant academic research and scientific papers

Aza-Claisen rearrangement of 2-C-hydroxymethyl glycals as a versatile strategy towards synthesis of isofagomine and related biologically important azasugars

Synthesis of isofagomine has been achieved by implementation of aza-Claisen rearrangement of 2-C-hydroxymethyl glycals as a key step. The above rearrangement has also been utilized in the synthesis of biologically important polyhydroxylated piperidine frameworks such as isogalactofagomine, ent-isogalactofagomine and their analogues and some other azasugars as glycosidase inhibitors. The Royal Society of Chemistry 2012.