1369849-16-0Relevant academic research and scientific papers
Synthesis, crystal structure and biological activity of a novel 1,2,3-thidiazole compound
Ke, Wei,Sun, Na-Bo,Wu, Hong-Ke
, p. 1233 - 1238 (2013/09/23)
A new 1,2,3-thiadiazole compound was synthesized and characterized by 1H NMR, MS and HRMS. The crystal structure of the title compound (C12H11ClN2O4S2, Mr = 346.80) has been determined by single-crystal X-ray diffraction. The crystal is of triclinic, space group P-1 with a = 8.4425(17) A, b = 8.9801(18) A, c = 9.859(2) A, α = 84.36(3) °, β = 86.71(3)°, γ = 83.25(3)°, V = 737.9(3)A3, Z = 2, F(000) = 356, Dc = 1.561 g/cm3, μ = 0.557 mm-1, the final R1 = 0.0380 and wR2 = 0.0982 for 2160 observed reflections with I > 2σ(I). A total of 12585 reflections were collected, of which 2601 were independent (Rint = 0.0364). The herbicidal activity of title compound was determined, the results showed the title compound displayed excellent herbicidal activity against Brassica campestris.
Synthesis, bioactivity and DFT structure-activity relationship study of novel 1,2,3-thiadiazole derivatives
Liu, Xing-Hai,Zhao, Wei-Guang,Wang, Bao-Lei,Li, Zheng-Ming
, p. 1999 - 2008 (2013/02/23)
A series of novel 1,2,3-thiadiazole derivatives were designed and synthesized. Their structures were characterized by 1H NMR, MS and HRMS. The bioactivity tests indicated that compound 9b exhibits a favorable KARI inhibition rate, and some of these novel compounds also showed moderate herbicidal activity against Brassica campestris. Springer Science+Business Media B.V. 2012.
