1369862-26-9Relevant academic research and scientific papers
Iron-catalyzed kinetic resolution of N-sulfonyl oxaziridines
Williamson, Kevin S.,Sawicki, James W.,Yoon, Tehshik P.
, p. 3524 - 3527 (2014/08/18)
We have developed a highly selective kinetic resolution of N-sulfonyl oxaziridines. This reaction utilizes an inexpensive and easily synthesized iron bis(oxazoline) catalyst to promote the efficient rearrangement of oxaziridines to the corresponding N-sulfonyl imides; no sacrificial reagents are required to effect this resolution. This process is readily translated to gram scale, which provides a practical method for the preparation of structurally diverse, enantiopure N-sulfonyl oxaziridines for use as reagents in organic synthesis.
Hf(IV)-catalyzed enantioselective epoxidation of N-alkenyl sulfonamides and N-tosyl imines
Olivares-Romero, Jose Luis,Li, Zhi,Yamamoto, Hisashi
supporting information; experimental part, p. 5440 - 5443 (2012/05/20)
Asymmetric epoxidation of allylic and homoallylic amine derivatives catalyzed by Hf(IV)-bishydroxamic acid complexes is described. Under similar conditions, aldimine and ketimine produced oxaziridines. The sulfonyl group is demonstrated to be an effective directing group for these transformations.
