1369892-14-7Relevant academic research and scientific papers
Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi
Martín-Escolano, Rubén,Moreno-Viguri, Elsa,Santivanez-Veliz, Mery,Martin-Montes, Alvaro,Medina-Carmona, Encarnación,Paucar, Rocío,Marín, Clotilde,Azqueta, Amaya,Cirauqui, Nuria,Pey, Angel L.,Pérez-Silanes, Silvia,Sánchez-Moreno, Manuel
, p. 5643 - 5663 (2018)
Chagas disease is a potentially life-threatening and neglected tropical disease caused by Trypanosoma cruzi. One of the most important challenges related to Chagas disease is the search for new, safe, effective, and affordable drugs since the current ther
Synthesis and pharmacological evaluation of carbamic acid 1-phenyl-3-(4-phenyl-piperazine-1-yl)-propyl ester derivatives as new analgesic agents
Chae, Eunhee,Yi, Hanju,Choi, Yeonjung,Cho, Hyeon,Lee, Kiho,Moon, Hongsik
scheme or table, p. 2434 - 2439 (2012/05/05)
A series of carbamic acid 1-phenyl-3-(4-phenyl-piperazine-1-yl)-propyl ester derivatives were synthesized through discovery strategies for balancing target-based in vitro screening and phenotypic in vivo screening. All the newly synthesized compounds were
