13699-45-1

Basic information

• Product Name: myristoyllysophosphatidylcholine
• Synonyms: myristoyllysophosphatidylcholine
• CAS NO: 13699-45-1
• Molecular Formula: C₂₂H₄₆NO₇P
• Molecular Weight: 467.58
• Mol File: 13699-45-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: myristoyllysophosphatidylcholine(CAS DataBase Reference)
• NIST Chemistry Reference: myristoyllysophosphatidylcholine(13699-45-1)
• EPA Substance Registry System: myristoyllysophosphatidylcholine(13699-45-1)

Safety Data

• Hazardous Substances Data: 13699-45-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H46NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-22(25)28-19-21(24)20-30-31(26,27)29-18-17-23(2,3)4/h21,24H,5-20H2,1-4H3

Upstream product

• 18194-24-6 dimyristoylphosphatidylcholine 
• 34688-34-1 glycerolcholine phosphate 
• 69205-89-6 myristic acid imidazolide 

Downstream Products

• 273931-53-6 C₃₂H₅₃N₂O₁₂P 
• 116113-36-1 1,1'-dimyristoyl-2,2'-<11,11'-bisundecanoyl>-sn-glycero-3-phosphocholine 

Relevant articles and documents

γ-Ray irradiation of liposomes of polymerizable phospholipids containing octadeca-2,4-dienoyl groups and characterization of the irradiated liposomes

The synthesis of a variety of polymerizable phospholipids containing the octadeca-2,4-dienoyl moiety on 2-acyl chains and the characteristics of liposomes containing those phospholipids of the γ-irradiation are described. We synthesized three different polymerizable phosphocholines that have different 1-acyl chain lengths with the octadeca-2,4-dienoyl moiety on the 2- acyl chain: myristoyl (MODPC), palmitoyl (PODPC) and stearoyl (SODPC). The liposomes were prepared by extrusion through polycarbonate filters with a pore size of 0.2 μm, and were polymerized by γ-irradiation with various dose rates. The polymerization rate increased in the order SODPC>MODPC>PODPC. The mechanism of the polymerization of SODPC was the same as that of 1,2-bis- [(E,E)-octadeca-2,4-dienoyl]-sn-glycero-3-phosphocholine (DODPC), but differed from that of MODPC and PODPC. Freeze-thaw testing was used to evaluate the stability of the polymerizable liposomes. The MODPC liposome was more stable than other monofunctional liposomes. For similar irradiation, the polymerization behavior of the liposomes was significantly affected by the 1- acyl length.

Polymer-supported bases. XII. Regioselective synthesis of lysophospholipids using polymer-supported bicyclic amidines or guanidines

1-Acylphosphatidylcholines were prepared in good yields by the regioselective monoacylation of L-α-glycerophosphorylcholine with acylimidazoles in the presence of polymer-supported bicyclic amidine of guanidine.