1369964-75-9

Upstream product

• 771-40-4 2-methyl-4H-thiochromen-4-one 
• 1345691-05-5 4-oxo-3-phenyl-4H-thiochromene-2-carbaldehyde 
• 1369964-76-0 C₁₆H₁₀O₄S 
• 1369964-77-1 C₂₃H₁₈N₂O₅S₂ 
• 20848-85-5 2-methyl-3-phenyl-4H-thiochromen-4-one 
• 108-98-5 thiophenol 
• 140173-38-2 3-iodo-2-methyl-4H-benzothiopyran-4-one 

Downstream Products

• 1187758-96-8 (1,1-dioxido-4-oxo-3-phenyl-4H-thiochromen-2-yl)methyl diphenyl phosphate 
• 1187758-97-9 (1,1-dioxido-4-oxo-3-phenyl-4H-thiochromen-2-yl)methyl diethyl phosphate 
• 1369964-84-0 (1,1-dioxido-4-oxo-3-phenyl-4H-thiochromen-2-yl)methyl bis(2-ethylhexyl) phosphate 
• 1369964-88-4 bis((1,1-dioxido-4-oxo-3-phenyl-4H-thiochromen-2-yl)methyl) naphthalen-1-yl phosphate 
• 1369964-82-8 dibenzyl (1,1-dioxido-4-oxo-3-phenyl-4H-thiochromen-2-yl)methyl phosphate 
• 1369964-80-6 dibutyl (1,1-dioxido-4-oxo-3-phenyl-4H-thiochromen-2-yl)methyl phosphate 
• 1369964-86-2 2-(((5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)oxy)methyl)-3-phenyl-4H-thiochromen-4-one 1,1-dioxide 

Relevant academic research and scientific papers

Study of the Paternò–Büchi type photolabile protecting group and application to various acids

An efficient photolabile protecting group, thiochromone S,S-dioxides with the diazomethyl group for phosphate derivatives, amino acids and sulfonic acids was developed. Protection and photodeprotection reactions proceeded smoothly under mild conditions without any catalyst.1H NMR and HPLC spectra studies demonstrated the photolysis properties of the photolabile protecting group and gave an exact quantification of the released substrates. Specially, the photoproduct derived from the thiochromone derivatives following Paternò–Büchi type photo-cycloaddition showed high fluorescence intensity. This fluorescent characteristic demonstrated the photodeprotection progress also can be monitored by fluorescence spectra.

Novel photolabile protecting group for phosphate compounds

A novel photolabile protecting group, thiochromone S,S-dioxide, containing the diazomethyl group for protection of phosphate derivatives is described. Deprotection of the successfully protected phosphate derivatives proceeded smoothly under photoirradiation using an ultrahigh-pressure mercury lamp to recover the corresponding phosphates quantitatively, and the photoproduct derived from the thiochromone derivative showed high fluorescence intensity. Georg Thieme Verlag Stuttgart · New York.