1369969-32-3

Basic information

• Product Name: C₃₀H₃₈N₂O₈
• Synonyms: C₃₀H₃₈N₂O₈
• CAS NO: 1369969-32-3
• Molecular Weight: 554.64
• Mol File: 1369969-32-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₀H₃₈N₂O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₀H₃₈N₂O₈(1369969-32-3)
• EPA Substance Registry System: C₃₀H₃₈N₂O₈(1369969-32-3)

Safety Data

• Hazardous Substances Data: 1369969-32-3(Hazardous Substances Data)

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 1064604-21-2 methyl (2S,3aR,8aR)-[3a-bromo-(1,2,3,3a,8,8a)-hexahydropyrrolo[2,3-b]indole-1,8-di-tertbutoxycarbonyl]-2-carboxylate 
• 96238-68-5 tert-butyl (+)-(S)-3-[2-(tert-butoxycarbonylamino)-3-methoxy-3-oxopropyl]-1H-indole-1-carboxylate 

Relevant articles and documents

Silver-promoted Friedel-Crafts reaction: Concise total synthesis of (-)-ardeemin, (-)-acetylardeemin and (-)-formylardeemin

Total syntheses of multidrug resistant inhibitors (-)-acetylardeemin 2a, (-)-ardeemin 2b, and (-)-formylardeemin 3 have been achieved within 10 steps starting from bromopyrroloinoline 13. The key step involves direct alkylation of 13 with prenyl tributylstannane 11 to yield 12via a silver-promoted asymmetric Friedel-Crafts reaction. Highly efficient installation of the isoprenyl group allowed excellent overall yield. Moreover, the substrate scope of the asymmetric Friedel-Crafts reaction of 13 was expanded to include a variety of arenes 14 to afford natural product-like library analogues 15. The Royal Society of Chemistry 2012.