136997-48-3Relevant academic research and scientific papers
New pyrazol derivatives. Part 7: Synthesis of new pyrazolo[1,5-a]pyrimidines
Eisenacher,Pech,Bohm
, p. 580 - 581 (2007/10/02)
Keten-mercaptals like 3,3-dimethylthio-acrylic acid esters react with ethyl 3-aminopyrazol-4-carboxylate under formation of methylmercaptan followed by cyclisation to give esters of 2-methylthio-1H-1,4-dihydro-4-oxopyrazolo[1,5-a]pyrimidin-8-carboxylic acid. The remaining methylthio group can be substituted by amines.
