1370029-97-2Relevant academic research and scientific papers
1,3,4-Thiadiazole derivatives as selective inhibitors of iNOS versus nNOS: Synthesis and structure-activity dependence
López-Cara, Luisa C.,Carrión, M. Dora,Entrena, Antonio,Gallo, Miguel A.,Espinosa, Antonio,López, Ana,Escames, Germaine,Acu?a-Castroviejo, Darío,Camacho, M. Encarnación
, p. 129 - 139 (2012/07/03)
The synthesis of new compounds with a 1,3,4-thiadiazole structure, and their in vitro biological evaluation as inhibitors of both neuronal and inducible Nitric Oxide Synthase (nNOS and iNOS) is described. These compounds have been designed by an isosteric
