137003-76-0

Usage

Uses

Used in Pharmaceutical Industry:
(+/-)-5-Ethyl-2,2,2-triphenyl-1,2-λ⁵-oxaphospholan is used as a catalyst for facilitating organic synthesis reactions, which is crucial for the production of organic molecules with high levels of stereochemical control. This is particularly important in the development of pharmaceuticals, where precise molecular structures are necessary for efficacy and safety.
Used in Fine Chemical Industry:
In the fine chemical industry, (+/-)-5-Ethyl-2,2,2-triphenyl-1,2-λ⁵-oxaphospholan serves as a catalyst to enable the synthesis of complex organic molecules with specific spatial arrangements. This is essential for the production of high-quality specialty chemicals that require a high degree of stereochemical purity.
Used in Organic Synthesis Research:
(+/-)-5-Ethyl-2,2,2-triphenyl-1,2-λ⁵-oxaphospholan is utilized as a research tool in organic synthesis, where its unique properties allow chemists to explore new reaction pathways and develop innovative synthetic methods. This contributes to the advancement of chemical knowledge and the discovery of new compounds with potential applications across various fields.

Upstream product

• 106-88-7 ethyloxirane 
• 19493-09-5 Methylenetriphenylphosphorane 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Relevant academic research and scientific papers

A novel reaction of oxaphosphoranes leading to 7-membered cyclic vinylidene acetals

Reaction of oxaphosphoranes with paraformaldehyde yielded novel 7-membered cyclic vinylidene acetals in almost quantitative yield. Phosphonium betaines reacted with parformaldehyde to give new betaines, which further reacted with paraformaldehyde to afford olefins via Wittig reaction.

Synthesis of cyclic ethers from 3- and 4-hydroxyalkylphosphonium salts

The reaction of 6-methylene-1,3-dioxepanes derived from 3-hydroxyalkyltriphenylphosphonium salts and paraformaldehyde with trimethylsilyl trifluoromethanesulfonate in the presence of N,N- diisopropylethylamine yielded novel 4-formyltetrahydropyrans. 3-Met

Phosphine Alkylenes, 50. - On the Structure of 2,2,2-Triphenyl-1,2-λ5-oxaphospholanes

2,2,2-Triphenyl-1,2-λ5-oxaphospholanes (5a-h) were synthesized from methylene-triphenylphosphorane (1, R=H) and suitable epoxides (2a-g).Oxaphospholane 5e was subjected to an X-ray structural analysis, which showed a five-membered ring-structure with a trigonal-bipyramidal coordinate phosphorus atom.One phenyl group and the ring oxygen atom are apical ligands at phosphorus.According to the NMR spectra, oxaphospholanes have a ring structure in nonpolar solvents, whereas in polar solvents there exists an equilibrium with an open-chain form.Key Words: Phosphorus, tetra- and pentacoordinate / Oxaphospholanes / Trigonal-bipyramidal structure / Eqquilibrium of ring and betain structure in polar solvent