137018-12-3Relevant academic research and scientific papers
Halogen-metal exchange reactions of bromoaryl-substituted β-lactams
Geherty, Maryll,Melnyk, James,Chomsky, Keith,Hunt, David A.
, p. 4934 - 4936 (2013/09/02)
β-Lactams are quite susceptible to ring opening when exposed to nucleophilic reagents. The robustness of a variety of bromo- and iodoarenes containing electrophilic functional groups toward alkyllithium reagents during the halogen-lithium exchange process
Arenetricarbonylchromium Complexes as Chiral Auxiliaries: Asymmetric Synthesis of β-Lactams
Baldoli, Clara,Buttero, Paola Del
, p. 982 - 984 (2007/10/02)
A new enantioselective synthesis of β-lactams via condensation of optically pure ortho-substituted benzylideneaminetricarbonylchromium complexes with ester-enolates is reported; the enantiomeric excess is higher than 98percent.
