137022-94-7Relevant academic research and scientific papers
Intramolecular Addition of Aryl Radicals to Vinylogous Urethanes: Studies Toward Preparation of the Oxindole Portion of Gelsemine
Hart, David J.,Wu, Shung C.
, p. 4099 - 4102 (1991)
Free radical cyclization of vinylogous urethanes 5 and 12 gave spiro oxindoles 6 and 13 + 14, in 95percent and 84percent yields, respectively.Cyclization of projected gelsemine intermediate 19 resulted in the formation of oxindole 22 via a cyclization, 1,4-hydrogen atom transfer, reduction sequence.
