1370335-41-3

Upstream product

• 641571-13-3 3-(4-methyl-imidazol-1-yl)-5-trifluoromethylbenzoic acid 
• 72080-83-2 2-benzyloxycarbonylaminoethylamine 
• 77987-49-6 benzyl 2-hydroxyethylcarbamate 
• 134307-72-5 2-(((benzyloxy)carbonyl)amino)ethyl 1-methanesulfonate 
• 501-53-1 benzyl chloroformate 
• 146552-66-1 benzyl (2-azidoethyl)carbamate 

Downstream Products

• 1370335-61-7 C₁₄H₁₅F₃N₄O 
• 1261242-36-7 N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide 

Relevant academic research and scientific papers

Imidazothiazole-based potent inhibitors of V600E-B-RAF kinase with promising anti-melanoma activity: biological and computational studies

A series of imidazothiazole derivatives possessing potential activity against melanoma cells were investigated for molecular mechanism of action. The target compounds were tested against V600E-B-RAF and RAF1 kinases. Compound 1zb is the most potent agains

Broad-spectrum antiproliferative activity of a series of 6-(4-fluorophenyl)-5-(2-substituted pyrimidin-4-yl)imidazo[2,1-b]thiazole derivatives

This article described the synthesis and in vitro antiproliferative activities a series of 6-(4-fluorophenyl)-5-(2-substituted pyrimidin-4-yl)imidazo[2,1-b]thiazole derivatives. The nine target compounds were tested for in vitro antitumor effect against a

Synthesis of new 6-(4-Fluorophenyl)-5-(2-substituted pyrimidin-4-yl) imidazo[2,1-b] thiazole derivatives and their antiproliferative activity against melanoma cell line

Synthesis of a new series of pyrimidinyl-imidazo[2,1-b]thiazole derivatives is described. Their antiproliferative activity against A375 human melanoma cell line was tested and the effect of substituents on the pyrimidinyl ring side chain was investigated.