1370337-75-9Relevant academic research and scientific papers
Rapid development and scale-up of a 1 H -4-substituted imidazole intermediate enabled by chemistry in continuous plug flow reactors
May, Scott A.,Johnson, Martin D.,Braden, Timothy M.,Calvin, Joel R.,Haeberle, Brian D.,Jines, Amy R.,Miller, Richard D.,Plocharczyk, Edward F.,Rener, Gregory A.,Richey, Rachel N.,Schmid, Christopher R.,Vaid, Radhe K.,Yu, Hannah
, p. 982 - 1002 (2012)
The development of reactions in a continuous fashion in plug flow tube reactors (PFR) offers unique advantages to the drug development and scale-up process and can also enable chemistry that would be difficult to perform via batch processing. Herein, we r
