137035-08-6

Basic information

• Product Name: (R)-(+)-2-(4-chlorophenyl)-3,4-dihydro-2H-1,4-benzothiazine
• Synonyms: (R)-(+)-2-(4-chlorophenyl)-3,4-dihydro-2H-1,4-benzothiazine
• CAS NO: 137035-08-6
• Molecular Weight: 261.775
• Mol File: 137035-08-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-(+)-2-(4-chlorophenyl)-3,4-dihydro-2H-1,4-benzothiazine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-2-(4-chlorophenyl)-3,4-dihydro-2H-1,4-benzothiazine(137035-08-6)
• EPA Substance Registry System: (R)-(+)-2-(4-chlorophenyl)-3,4-dihydro-2H-1,4-benzothiazine(137035-08-6)

Safety Data

• Hazardous Substances Data: 137035-08-6(Hazardous Substances Data)

Relevant articles and documents

Thiazine (or oxazine) derivatives and preparation thereof

Thiazine derivatives of the formula [I]: STR1 wherein R1, R2, R4 and R5 are each hydrogen atom; R3 is hydrogen atom or a halogen atom; X is sulfur atom; R6 is naphthyl, a sulfur-containing monoheterocyclic group or a substituted phenyl; Z1 is two hydrogen atoms; Z2 is oxygen atom; A is a lower alkylene; R7 and R8 are the same or different and are each i) hydrogen atom, ii) a lower alkyl, iii) a lower alkenyl, iv) a lower alkynyl, or v) a lower alkyl which is substituted by a substituted phenyl, or both form together with the adjacent nitrogen atom a nitrogen-containing monoheterocyclic group; except for the compound [I] wherein R1, R2, R3, R4 and R5 are each hydrogen atom, X is sulfur atom, R6 is a halogenophenyl, Z1 is two hydrogen atoms, Z2 is oxygen atom, A is a lower alkylene, R7 and R8 are the same or different and each a lower alkyl; or a pharmaceutically acceptable salt thereof, which have calcium antagonistic activity within the cerebral tissues and are useful for prophylaxis and treatment of ischemic encephalopathia.