1370458-45-9Relevant academic research and scientific papers
Asymmetric and highly stereoselective synthesis of the def-ring moiety of (-)-FR182877 and its derivative inducing mitotic arrest
Kobayakawa, Yu,Mori, Yusuke,Okajima, Hideki,Terada, Yasuhiko,Nakada, Masahisa
, p. 2086 - 2089 (2012/06/29)
The asymmetric and highly stereoselective synthesis of compound 1, which corresponds exactly to the DEF-ring moiety of (-)-FR182877, and the biological activities of its derivatives are described. All derivatives of 1 showed no activity in the tubulin pol
