137046-97-0

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 137047-02-0 4-(2-Bromo-4,5-methylenedioxybenzyl)dihydro-2(3H)-furanone 
• 120-57-0 piperonal 
• 137047-01-9 4-<2-Bromo-4,5-methylenedioxy-α-cyano-α-(1-ethoxyethoxy)benzyl>dihydro-2(3H)-furanone 
• 137047-00-8 2-(2-Bromo-4,5-methylenedioxyphenyl)-2-(1-ethoxyethoxy)acetonitrile 
• 137046-96-9 4-(2-Bromo-4,5-methylenedioxybenzoyl)dihydro-2(3H)-furanone 
• 137046-98-1 (6-Bromo-benzo[1,3]dioxol-5-yl)-trimethylsilanyloxy-acetonitrile 
• 137046-99-2 (6-Bromo-benzo[1,3]dioxol-5-yl)-hydroxy-acetonitrile 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 

Downstream Products

• 137047-03-1 erythro-trans-4-(2-Bromo-4,5-methylenedioxybenzyl)-3-(α-chloro-3,4,5-trimethoxybenzyl)dihydro-2(3H)-furanone 
• 137047-03-1 threo-trans-4-(2-Bromo-4,5-methylenedioxybenzyl)-3-(α-chloro-3,4,5-trimethoxybenzyl)dihydro-2(3H)-furanone 

Relevant academic research and scientific papers

SYNTHETIC STUDIES ON PODOPHYLLUM LIGNANS: TRIBUTYLTIN HYDRIDE-INDUCED RADICAL CYCLIZATION AND INTRAMOLECULAR HECK REACTION OF α-BENZYLIDENE-β-(o-BROMOBENZYL)-γ-LACTONES

Tributyltin hydride-induced radical cyclization of the (Z)-α-benzylidene-β-(o-bromobenzyl)-γ-lactone (16) gave the 6-endo cyclization product, (+/-)-deoxyisopicropodophyllin (18), and the 5-exo cyclization product (19).On the other hand, the intramolecular Heck reaction of 16 provided (+/-)-γ-apopicropodophyllin (20) as a sole cyclization product.