1370463-65-2Relevant academic research and scientific papers
Efficient synthesis of DOPA analogues in pepticinnamins E via asymmetric catalytic hydrogenation of dehydroamino esters
Sun, De-Qun,Sun, Li,Luo, Min
experimental part, p. 1731 - 1734 (2012/08/28)
One practical synthetic procedure with five steps was developed to prepare a series of N-protected-2-(diethoxyphosphoryl)glycinates with good yields, which was treated with aldehydes under mild condition to give different dehydroamino esters with high yields and excellent Z/E selectivity. The subsequently homogeneous enantioselective hydrogenation of the dehydroamino esters affords a series of new DOPA analogues.
