137048-94-3

Basic information

• Product Name: BUTYL-(3-MORPHOLIN-4-YL-PROPYL)-AMINE
• Synonyms: BUTYL-(3-MORPHOLIN-4-YL-PROPYL)-AMINE;ART-CHEM-BB B023065;AKOS B023065;TIMTEC-BB SBB007156
• CAS NO: 137048-94-3
• Molecular Formula: C11H24N2O
• Molecular Weight: 200.32
• Mol File: 137048-94-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BUTYL-(3-MORPHOLIN-4-YL-PROPYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BUTYL-(3-MORPHOLIN-4-YL-PROPYL)-AMINE(137048-94-3)
• EPA Substance Registry System: BUTYL-(3-MORPHOLIN-4-YL-PROPYL)-AMINE(137048-94-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 137048-94-3(Hazardous Substances Data)

Relevant articles and documents

Synthesis and pharmacological evaluation of 1,1,3-substituted urea derivatives as potent TNF-α production inhibitors

A three substituted urea derivative, SA13353 (compound 1a), exhibited potent inhibitory activity against lipopolysaccharide (LPS)-induced TNF-α production. We focused on the 1,1-substituted moiety (R1 and R 2) of SA13353 and investigated substituent effects of this moiety on LPS-induced TNF-α production by oral administration in rats. The synthesis of the urea derivatives was performed rapidly in a one-pot manner using a manual synthesizer. Several compounds containing hydrophobic substituents at this moiety showed more potent inhibitory activities than SA13353.