1370525-64-6Relevant academic research and scientific papers
Investigations into the mechanisms of pyridine ring cleavage in vismodegibs
Khojasteh, S. Cyrus,Yue, Qin,Ma, Shuguang,Castanedo, Georgette,Chen, Jacob Z.,Lyssikatos, Joseph,Mulder, Teresa,Takahashi, Ryan,Ly, Justin,Messick, Kirsten,Jia, Wei,Liu, Lichuan,Hop, Cornelis E. C. A.,Wong, Harvey
, p. 343 - 351 (2014)
Vismodegib (Erivedge, GDC-0449) is a first-in-class, orally administered small-molecule Hedgehog pathway inhibitor that is approved for the treatment of advanced basal cell carcinoma. Previously, we reported results from preclinical and clinical radiolabe
