1370550-63-2Relevant academic research and scientific papers
One-pot isocyanide-based five-component reaction: Synthesis of highly functionalized N-cyclohexyl-2-(2,4-dioxo-2,3,4,5 tetrahydro-1H-benzo[b][1,5]diazepin-3-yl)-2-phenylacetamides
Mousavi Faraz, Sajjad,Rahmati, Abbas,Mirkhani, Valiollah
, p. 557 - 565 (2017/03/15)
A new protocol has been developed for the efficient synthesis of structurally diverse N-cyclohexyl-2-(2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,5]diazepin-3-yl)-2-phenylacetamides through a one-pot, five-component condensation reaction of an aromatic diamine, an aromatic aldehyde, an isocyanide, ethyl malonyl chloride, and water in dichloromethane with good yields, at ambient temperature, in the presence of MgCl2 as a catalyst.
Synthesis of new tetrahydro-1,5-benzodiazepin-3-yl-2-phenylacetamides via isocyanide-based multicomponent reactions
Astaraki, Ali Mohammad,Bazgir, Ayoob
, p. 175 - 178 (2013/03/13)
New tetrahydro-1H-1,5-benzodiazepin-2-phenylacetamides were synthesized in good yields by a four-component reaction of benzylidene Meldrum's acid, benzene-1,2-diamines, isocyanides, and water in CH2Cl2 at room temperature.
Isocyanide-based five-component synthesis of 2-Aryl-2-(2,3,4,5-tetrahydro- 2,4-dioxo-1H-1,5-benzodiazepin-3-yl)acetamides (=α-Aryl-2,3,4,5- tetrahydro-2,4-dioxo-1H-1,5-benzodiazepine-3-acetamides)
Akbarzadeh, Roya,Amanpour, Tayebeh,Soorki, Ali Abolhasani,Bazgir, Ayoob
experimental part, p. 483 - 490 (2012/05/04)
An efficient and simple method for the synthesis of new 2-aryl-2-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)acetamides (=α-aryl-2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepine-3-acetamides) by a five-component condensation reaction of benz
