1370550-67-6

Basic information

• Product Name: N-(2,6-dimethylphenyl)-2-(2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(3-methoxyphenyl)acetamide
• Synonyms: N-(2,6-dimethylphenyl)-2-(2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(3-methoxyphenyl)acetamide
• CAS NO: 1370550-67-6
• Molecular Weight: 443.502
• Mol File: 1370550-67-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(2,6-dimethylphenyl)-2-(2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(3-methoxyphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,6-dimethylphenyl)-2-(2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(3-methoxyphenyl)acetamide(1370550-67-6)
• EPA Substance Registry System: N-(2,6-dimethylphenyl)-2-(2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-2-(3-methoxyphenyl)acetamide(1370550-67-6)

Safety Data

• Hazardous Substances Data: 1370550-67-6(Hazardous Substances Data)

Upstream product

• 119072-54-7 2,6-dimethylphenyl isonitrile 
• 591-31-1 3-methoxy-benzaldehyde 
• 95-54-5 1,2-diamino-benzene 
• 6258-45-3 5-[(3-methoxyphenyl)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 2033-24-1 cycl-isopropylidene malonate 

Relevant articles and documents

One-pot isocyanide-based five-component reaction: Synthesis of highly functionalized N-cyclohexyl-2-(2,4-dioxo-2,3,4,5 tetrahydro-1H-benzo[b][1,5]diazepin-3-yl)-2-phenylacetamides

A new protocol has been developed for the efficient synthesis of structurally diverse N-cyclohexyl-2-(2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,5]diazepin-3-yl)-2-phenylacetamides through a one-pot, five-component condensation reaction of an aromatic diamine, an aromatic aldehyde, an isocyanide, ethyl malonyl chloride, and water in dichloromethane with good yields, at ambient temperature, in the presence of MgCl2 as a catalyst.

Isocyanide-based five-component synthesis of 2-Aryl-2-(2,3,4,5-tetrahydro- 2,4-dioxo-1H-1,5-benzodiazepin-3-yl)acetamides (=α-Aryl-2,3,4,5- tetrahydro-2,4-dioxo-1H-1,5-benzodiazepine-3-acetamides)

An efficient and simple method for the synthesis of new 2-aryl-2-(2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepin-3-yl)acetamides (=α-aryl-2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepine-3-acetamides) by a five-component condensation reaction of benz