137056-26-9Relevant articles and documents
The Reaction of 2-Aminothiophene-3-carbonitriles with Heterocumulenes
Gewald, K.,Jeschke, T.,Gruner, M.
, p. 229 - 236 (2007/10/02)
The reaction of 2-aminothiophene-3-carbonitriles (1) with phenyl isothiocyanate does not yield the expected thienopyrimidine derivatives but the substituted dithienopyrimidopyrimid-7-thiones (4).The compounds 4 also may be synthesized from 1 and thiophosgene.Analogously, from 1 and phenyl isocyanate the substituted dithienopyrimidopyrimid-7-ones (9) arise in small yields.They are better obtainable from 1 and phosgene.Carbon disulphide reacts with 1 in pyridine to form a mixture of the thienopyrimid-2,4-dithione (10) and the condensed compound 4.The ratio of of products depends on the substituents in the 4,5-position of 1.The structures are investigated by n.m.r.-spectroscopy.