1370590-75-2Relevant academic research and scientific papers
Klebsiella pneumoniae (NBRC 3319) mediated asymmetric reduction of α-substituted β-oxo esters and its application to the enantioiselective synthesis of small-ring carbocycle derivatives
Bhuniya, Rajib,Mahapatra, Tridib,Nanda, Samik
, p. 1597 - 1602 (2012)
Ketoreductases from Klebsiella pneumoniae (NBRC 3319) selectively reduce several 2-substituted ethyl 3-oxobutyrates to yield the corresponding syn-β-hydroxy esters with remarkable stereocontrol (de > 99%, ee > 99%). The enantiopure hydroxy oxo esters were
