1370641-43-2Relevant articles and documents
Preparation method of novel boron-containing adjuvant drug key intermediate chiral alpha-amino borate
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Paragraph 0074-0077, (2020/10/06)
The invention belongs to the technical field of drug synthesis and preparation, and particularly relates to a preparation method of a novel boron-containing adjuvant drug key intermediate chiral alpha-amino borate. The preparation method has the advantages of cheap and easily available raw materials, simple operation, mild reaction, simple post-reaction treatment, high optical purity of the product and the like, the final product does not need to be further purified, the industrialization requirement is met, and the preparation method has very remarkable economic practicability and developmentpotential.
Oxazolidinone-promoted, torquoselective Nazarov cyclizations
Kerr, Daniel J.,Miletic, Michael,Chaplin, Jason H.,White, Jonathan M.,Flynn, Bernard L.
supporting information; experimental part, p. 1732 - 1735 (2012/06/04)
Oxazolidinones are powerful promoters of the Nazarov reaction, enabling the cyclization of conventionally resistant substrates to be achieved under mild conditions. They exert excellent regio-and torquoselective control in both the conventional Nazarov reaction giving cyclopentenones and in the "interrupted" Nazarov reaction, giving more highly substituted multistereocenter containing products.