1370687-51-6

Basic information

• Product Name: C₁₆H₂₅NO₄
• Synonyms: C₁₆H₂₅NO₄
• CAS NO: 1370687-51-6
• Molecular Weight: 295.379
• Mol File: 1370687-51-6.mol

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₅NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₅NO₄(1370687-51-6)
• EPA Substance Registry System: C₁₆H₂₅NO₄(1370687-51-6)

Safety Data

• Hazardous Substances Data: 1370687-51-6(Hazardous Substances Data)

Upstream product

• 2043-61-0 cyclohexanecarbaldehyde 
• 101822-05-3 cyclohexane-spiro-2'-(5'-chloromethyl-1',3'-dioxolan-4'-one) 
• 94034-57-8 cyclohexanespiro-2'-(-5'-methylene-1',3'-dioxolan-4'-one) 
• 1370639-67-0 C₂₈H₄₃NO₉ 
• 1370639-66-9 C₁₅H₁₈O₃S 

Downstream Products

• 1370639-68-1 C₁₆H₂₅NO₄*ClH 
• 219310-11-9 (R)-3-Amino-3-cyclohexyl-propionic acid; hydrochloride 

Relevant articles and documents

Enantioselective, chromatography-free synthesis of β3-Amino acids with natural and unnatural side chains

β3-Amino acids are key components of some pharmaceuticals, excellent surrogates for metabolically labile α-amino acids, and building blocks for chiral heterocycles. Unfortunately they are not easily accessible in enantiomerically pure form, especially when possessing unnatural side chains. A flexible, chromatography-free process for the synthesis of enantiopure β3-amino acids possessing natural and unnatural side chains is described. The procedure uses inexpensive starting materials and reagents and offers a good alternative to the hazardous and expensive Arndt-Eistert homologation of enantiopure α-amino acids. Its utility has been demonstrated with the preparative scale synthesis of two valuable β3-amino acids possessing unnatural side chains.